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Buspirone, sold under the name Buspar among others, is an anxiolytic medication primarily used for the treatment of generalized anxiety disorder. Unlike benzodiazepines, buspirone does not produce significant sedation, dependence, or withdrawal symptoms. Easy-to-read patient tips for buspirone covering how it works, benefits, risks, and best practices. Buspirone is an azapirone, commonly used with an SNRI to treat anxiety. Learn more about buspirone's side effects, drug interactions, administration and more, including how buspirone compares to Xanax for anxiety treatment. BuSpar is rapidly absorbed in man and undergoes extensive first-pass metabolism. In a radiolabeled study, unchanged buspirone in the plasma accounted for only about 1% of the radioactivity in the plasma. 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Generic name: buspirone (byoo SPYE rone) Tablets: 5 mg, 7.5 mg, 10 mg, 15 mg, 30 mg Brand name: Bucapsol® Capsules: 7.5 mg, 10 mg, 15 mg All FDA warnings are at the end of this fact sheet. Please consult them before taking this medication. What Is Buspirone And What Does It Treat? Buspirone is in a class of medications called anti-anxiety medications. Buspirone is not related to other anti … What is buspirone and what does it treat? Buspirone is in a class of medications called anti-anxiety medications. Buspirone is not related to other anti-anxiety medications, such as benzodiazepines, barbiturates or other sedative/ anxiolytic drugs. It is approved for the treatment of generalized anxiety disorder (GAD). Buspirone HCI is an anti-anxiety medication prescribed for the treatment of some behavior disorders, especially when the behavior is related to fear or phobias. Like most anti-anxiety drugs, Buspirone HCI works by modifying chemicals in the brain to help reduce anxiety. 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