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Read more about the prescription drug allopurinol (Zyloprim, Aloprim). Additional Information How should I take Allopurinol? Before taking Allopurinol, you should read the manufacturer's printed Patient Information Leaflet (PIL) from inside the pack. It will give you more information about Allopurinol and provide you with a full list of the side effects which you may experience from taking it. Compare Allopurinol prices at 60,000+ US pharmacies. Get a free Rx.com coupon and save up to 90% on your prescription. allopurinol dosing, contraindications, interactions, side effects, adverse reactions, and pill pictures. Yes, Allopurinol use may cause liver problems. The doctor may advise to get your blood tests done to check how well your liver is working before and during treatment with Allopurinol. Inform your doctor if you experience symptoms like fatigue, loss of appetite for several days or longer, pain, aching, or tenderness on the right side of the abdomen. 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